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US CDC gets new acting director as leadership turmoil leaves agency reeling

US CDC gets new acting director as leadership turmoil leaves agency reeling
Jim O’Neill with Robert F. Kennedy Jr. (AP)
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Updated 29 August 2025

US CDC gets new acting director as leadership turmoil leaves agency reeling

US CDC gets new acting director as leadership turmoil leaves agency reeling

NEW YORK: The nation’s top public health agency was left reeling Thursday as the White House worked to expel the Centers for Disease Control and Prevention director and replace her with a top adviser to Health Secretary Robert F. Kennedy Jr.
The turmoil triggered rare bipartisan alarm as Kennedy tries to advance anti-vaccine policies that are contradicted by decades of scientific research.
Two administration officials said Jim O’Neill, a former investment executive, would supplant Susan Monarez, a longtime government scientist. O’Neill worked at the Department of Health and Human Services under President George W. Bush, but he does not have a medical background. The officials requested anonymity to discuss personnel decisions before a public announcement.
A flashpoint is expected in the coming weeks as a key advisory committee, which Kennedy has reshaped with vaccine skeptics, is expected to issue new recommendations on immunizations. The panel is scheduled to review standard childhood shots for measles, hepatitis and other diseases.
Two Republican senators called for congressional oversight and some Democrats said Kennedy should be fired. He is scheduled to testify on Capitol Hill on Sept. 4.
No explanation given for CDC director’s ouster
Kennedy has not explained the decision to oust Monarez less than a month after she was sworn in, but he warned that more turnover could be coming.
“There’s a lot of trouble at the CDC and it’s going to require getting rid of some people over the long term, in order for us to change the institutional culture,” Kennedy said at a news conference in Texas.
The White House has only said that Monarez was “not aligned with” President Donald Trump’s agenda.
Monarez’s lawyers said she refused “to rubber-stamp unscientific, reckless directives and fire dedicated health experts.” She is fighting her dismissal, saying the decision must come directly from Trump, who nominated her in March. The president has not said anything publicly about the matter.
Monarez tried to block political interference, departing CDC officials say
The saga began Wednesday night with the administration’s announcement that Monarez would no longer lead the CDC. In response, three officials — Dr. Debra Houry, Dr. Demeter Daskalakis and Dr. Daniel Jernigan — resigned from senior roles at the agency.
The officials returned to the office Thursday to collect their belongings, and hundreds of supporters gathered to applaud them as they left the Atlanta campus. There were bouquets of flowers, cheers and chants of “USA not RFK.”
Daskalakis, who resigned as head of the National Center for Immunization and Respiratory Diseases, said, “I fear that children will be hurt by poor decision making around vaccines.”
“You cannot dismantle public health and expect it to still work,” he said.
Jernigan stepped down as director of the National Center for Emerging and Zoonotic Infectious Diseases and Houry quit her post as the agency’s deputy director and chief medical officer.
Houry told The Associated Press that Monarez had tried to guard against political meddling in scientific research and health recommendations.
“We were going to see if she was able to weather the storm. And when she was not, we were done,” Houry said.
Dr. Richard Besser, a former CDC acting director, said Monarez told him that she had refused orders to fire her management team. He also said she refused to automatically sign off on any recommendations from Kennedy’s handpicked vaccine advisers.
“Dr. Monarez was one of the last lines of defense against this administration’s dangerous agenda,” said Besser, now president of the Robert Wood Johnson Foundation, which helps support The Associated Press Health and Science Department.
Health agencies have faced turmoil since Trump took office
The CDC has long been the target of controversy, particularly during the COVID-19 pandemic, as the agency struggled to balance politics and public health.
The strife only increased this year with Kennedy elevating unscientific ideas at the Department of Health and Human Services, which oversees the CDC, while pushing waves of layoffs.
Earlier this month, a police officer was killed when a man opened fire at the agency’s headquarters because of anger over COVID-19 vaccines, which have been the subject of falsehoods and conspiracy theories. A memorial to the officer remains outside the building, close to where staff members gathered Thursday.
Monarez stands to become the shortest-serving director since the CDC was founded in 1946, exacerbating a leadership vacuum that has persisted since Trump took office. He initially chose David Weldon, a former Florida congressman who is a doctor and vaccine skeptic, but yanked the nomination in March.
Monarez was tapped next to lead the $9.2 billion agency while serving as its interim director. However, questions immediately emerged within Kennedy’s circle about her loyalty to the “Make America Healthy Again” movement, especially given her previous support of the COVID-19 vaccines that Kennedy has routinely criticized.
Vaccine panel changes prompt demands for new oversight
Kennedy rarely mentioned Monarez by name in the way he did other health agency leaders such as Mehmet Oz of the Centers for Medicare and Medicaid Services or Marty Makary of the Food and Drug Administration.
One issue has been Kennedy’s handling of the CDC’s Advisory Committee on Immunization Practices, a group of outside experts who make recommendations to the CDC director on how to use vaccines. The recommendations are then adopted by doctors, school systems, health insurers and others.
The panel is expected to meet next month, and Sen. Bill Cassidy, R-Louisiana, said any recommendations issued then will be “lacking legitimacy.”
“Serious allegations have been made about the meeting agenda, membership, and lack of scientific process being followed,” said Cassidy, who heads the Senate committee overseeing Kennedy’s department. He added that “these decisions directly impact children’s health and the meeting should not occur until significant oversight has been conducted.”
Cassidy, a doctor, provided crucial support for Kennedy’s nomination after saying Kennedy had assured him that he would not topple the nation’s childhood vaccination program.
And yet, according to a government notice, the committee on Sept. 18 will take up votes on vaccines that have been settled fixtures for children, including shots to protect against hepatitis B and a combination shot against measles, mumps, rubella and chickenpox.
Kennedy is a longtime leader in the anti-vaccine movement, and in June, he abruptly dismissed the entire panel, accusing members of being too closely aligned with manufacturers. He replaced them with a group that included several vaccine skeptics and then he shut the door to several doctors organizations that had long helped form vaccine recommendations.
Departing CDC officials worry science will be compromised
Houry and Daskalakis said Monarez had tried to make sure scientific safeguards were in place.
For example, she tried to replace the official who coordinated the panel’s meetings with someone who had more policy experience. Monarez also pushed to have slides and evidence reviews posted weeks before the committee’s meetings and have the sessions open to public comment, Houry said.
HHS officials nixed that and called Monarez to a meeting in Washington on Monday, Houry said.
Daskalakis described the situation as untenable.
“I came to the point personally where I think our science will be compromised, and that’s my line in the sand,” he said.
Medical and public health organizations said they worried about the future without Monarez in charge.
“The scientific community is beginning to draw a line in the sand and say, ‘No way,’” said Dr. Georges Benjamin, executive director of the American Public Health Association.


Germany to propose boosting Ukraine’s defenses at allies’ meet

Updated 4 sec ago

Germany to propose boosting Ukraine’s defenses at allies’ meet

Germany to propose boosting Ukraine’s defenses at allies’ meet
BERLIN: Germany will propose help to strengthen Ukraine’s air defenses as part of future security guarantees at a meeting of Kyiv’s allies Thursday, a government source told AFP.
Berlin, long the biggest supplier of military aid to Ukraine after the United States, would also offer other weaponry and military training but has shied away so far from promising to send peacekeeping troops.
The German source added that Berlin’s offer would be “subject to three conditions” — first among them that the United States also participates in offering security guarantees.
Secondly, Russia would have to “participate in negotiations” and, thirdly, there would have to be consensus within the coalition government and support from the German parliament.
The source confirmed a report in news magazine Der Spiegel that Germany would aim to strengthen Ukraine’s air defenses by 20 percent per year, with regard to the number of weapons systems and their effectiveness.
Kyiv’s offensive air capabilities would also be bolstered, including with long-range weapons such as cruise missiles that could be manufactured in Ukraine with financial and technological support.
Germany would also provide equipment for four mechanized Ukrainian infantry brigades, including hundreds of infantry fighting vehicles.
And it would continue training Ukrainian soldiers and work to tighten the integration of arms production between Ukraine and the rest of Europe.
German Chancellor Friedrich Merz has said it is premature to discuss the possible deployment of German peacekeeping troops to Ukraine, while not entirely ruling out the prospect.
“The most important security guarantee we can provide for the moment is sufficient support to the Ukrainian army in efforts to the defend the country,” Merz said on Tuesday.
A Russia-Ukraine ceasefire would first be necessary for Germany to send troops “and even then there would be strict conditions,” he told the Sat1 TV channel.
Ukrainian President Volodymyr Zelensky was attending Thursday’s Paris meeting of the “coalition of the willing” in person.
The grouping of 30 mainly European states aims to demonstrate to US President Donald Trump that it is ready to offer security guarantees to Ukraine, provided Washington gives sufficient backup and puts pressure on Russia.
Merz and British Prime Minister Keir Starmer are expected to join the meeting remotely via videoconference.

Kim Jong Un has brought his daughter to Beijing. What to know about the possible North Korean heir

Kim Jong Un has brought his daughter to Beijing. What to know about the possible North Korean heir
Updated 32 min 17 sec ago

Kim Jong Un has brought his daughter to Beijing. What to know about the possible North Korean heir

Kim Jong Un has brought his daughter to Beijing. What to know about the possible North Korean heir
  • Since 2022, Kim Jong Un has showcased his daughter at a growing number of major public events tied to his nuclear-armed military, fueling speculation she is being primed as the country’s next leader

SEOUL: North Korean leader Kim Jong Un has brought his young daughter on his most significant foreign trip in years, a trip to China that marks his latest attempt to break out of isolation and bolster his position by balancing between traditional allies Moscow and Beijing.
The girl is believed to be named Kim Ju Ae and is around 12 or 13 years old. Not much else is known about her.
Since 2022, Kim Jong Un has showcased her at a growing number of major public events tied to his nuclear-armed military, fueling speculation she is being primed as the country’s next leader.
Kim’s daughter’s name and age are unconfirmed
While North Korean state media have described Kim’s daughter as “beloved” and “respected,” they have never called her by name.
The assumption that the girl’s name is Ju Ae is based on an account by former NBA champion Dennis Rodman where he recalled holding Kim Jong Un’s baby daughter during a trip to Pyongyang in 2013.
Ju Ae’s exact age is unconfirmed but South Korean intelligence officials believe she was born in 2013.
In a closed-door briefing to lawmakers in 2023, South Korea’s main spy agency said it believes Kim Jong Un and his wife Ri Sol Ju also have an older son and a younger third child whose gender is unknown.
Kim Jong Un beamed as he stepped out of his family’s iconic green armored train to shake hands with senior Chinese officials upon arrival in Beijing on Tuesday. He was closely followed by Ju Ae.
Dressed in a navy pantsuit with her hair styled in a half-updo, a look reminiscent of her mother’s public appearances, Ju Ae stood in front of senior North Korean officials, including Foreign Minister Choe Son Hui.
However, she did not make a public appearance the next day as her father shared center stage with Chinese President Xi Jinping and Russian President Vladimir Putin in a massive military parade at Tiananmen Square. The parade demonstrated a deepening alignment between Washington’s adversaries.
She’s being increasingly showcased in her father’s events
Kim Jong Un chose to publicly unveil his little-known daughter at a major military event — a test launch of an intercontinental ballistic missile — in November 2022.
State media released a series of photos of Kim and his daughter at the event, marking the first time her image was made public. She wore a white coat and red shoes as she watched a soaring missile from a distance and walked hand-in-hand with her father.
The missile test marked the first in a series of major military events where Kim Jong Un displayed his daughter. Her carefully-crafted appearances have included missile tests, military parades, and the launch of a naval destroyer in April, an event hailed as a major step in expanding North Korea’s nuclear arsenal. Kim Jong Un has recently expanded his daughter’s public appearances beyond military events to include some of his most ambitious economic projects and cultural events, including the opening of a beach resort in June.
Her trip to Beijing fuels speculation she is the future heir
Ju Ae’s increasing number of public appearances and presence in state media has led to speculation that she is being primed as her father’s successor. The theory has been further fueled by her first known foreign trip to China.
South Korea’s National Intelligence Service issued a careful assessment last year that it views Ju Ae as her father’s likely successor, citing a comprehensive analysis of her public activities and the state protocols provided to her.
However, the spy agency said there are still various possibilities regarding North Korea’s power succession process because Kim Jong Un, 41, is still young, has no major health issues and has other children.
Some South Korean officials and experts initially expressed doubts over Ju Ae as the future heir, citing North Korea’s male-nominated power structure and Confucian influence.
Since its foundation in 1948, North Korea has been successively ruled by male members of the Kim family. Kim Jong Un inherited power upon his father Kim Jong Il’s death in late 2011. Kim Jong Il took over power after his father and state founder Kim Il Sung died in 1994.
North Korea’s state media have yet to make any direct comments on a power succession plan beyond Kim Jong Un. It has also not commented on whether Ju Ae has any siblings.


China says it does not target any third party in ties with others

China says it does not target any third party in ties with others
Updated 04 September 2025

China says it does not target any third party in ties with others

China says it does not target any third party in ties with others

BEIJING: China does not target any third party while developing diplomatic ties with other countries, its foreign ministry said on Thursday, responding to US President Donald Trump’s comment that China, Russia and North Korea were conspiring against the US
In a post directed at Chinese President Xi Jinping on Truth Social as a massive military parade kicked off in Beijing on Wednesday, Trump highlighted the US role in helping China secure its freedom from Japan during World War Two.
“Please give my warmest regards to Vladimir Putin, and Kim Jong Un, as you conspire against the United States of America,” Trump added.


Afghanistan earthquake death toll climbs as aid runs thin

Afghanistan earthquake death toll climbs as aid runs thin
Updated 04 September 2025

Afghanistan earthquake death toll climbs as aid runs thin

Afghanistan earthquake death toll climbs as aid runs thin
  • Humanitarian needs are “vast and growing rapidly,” said aid group the International Federation of Red Cross and Red Crescent Societies (IFRC)
  • The United Nations has warned the toll could rise with people still trapped under rubble as time runs out for survivors

KABUL/NURGAL: Rescue workers and volunteers in eastern Afghanistan are still pulling bodies from the rubble days after powerful earthquakes devastated mountainous provinces bordering Pakistan, with Taliban authorities reporting the death toll has surpassed 1,457 and could rise further. More than 3,700 people have been injured and over 6,700 homes destroyed.

The first quake, measuring 6.0 in magnitude, struck on Sunday at a shallow depth of 10 km, making it one of the deadliest in decades. A second tremor of 5.5 magnitude on Tuesday triggered landslides, blocking access to remote villages in Kunar and Nangarhar provinces and complicating rescue efforts. Entire households were wiped out in some areas, and survivors have been left to sift through rubble with pickaxes and carry bodies on woven stretchers.

“Everything we had has been destroyed,” said Aalem Jan, a survivor from Kunar. “Our house collapsed, and all our belongings and possessions were lost. The only remaining things are these clothes on our backs.”

While most cut-off villages have now been reached, hopes of finding survivors are fading quickly. “Many survivors are still believed to be trapped beneath collapsed homes, and the window for finding them alive is rapidly closing,” the World Health Organization (WHO) warned.

Aid Shortfalls

Relief efforts face steep challenges. Rockfalls and poor infrastructure have slowed aid deliveries, while decades of war, poverty, and shrinking foreign assistance have left Afghanistan ill-prepared for large-scale disasters. The WHO said local health care services are “under immense strain” and appealed for $4 million to expand emergency operations, while also pointing to a critical funding gap for trauma supplies and medicines.

The UN World Food Programme (WFP) said it has resources to support survivors for just four more weeks, warning of a looming cutoff. Other aid groups stressed the need for long-term donor commitments. “The earthquake should serve as a stark reminder: Afghanistan cannot be left to face one crisis after another alone,” said Jacopo Caridi of the Norwegian Refugee Council.

UN refugee chief Filippo Grandi estimated more than 500,000 people have been affected, with thousands displaced. The International Federation of Red Cross and Red Crescent Societies (IFRC) said humanitarian needs are “vast and growing rapidly.”

Meanwhile, Afghanistan faces overlapping crises: endemic poverty, severe drought, and the forced return of millions of Afghans from Pakistan and Iran since the Taliban’s 2021 takeover. Despite the disaster, Pakistan has resumed its push to expel Afghan migrants, with more than 6,300 crossing back into quake-hit Nangarhar province on Tuesday alone.

“Every hour counts,” said WHO emergency lead Jamshed Tanoli. “Hospitals are struggling, families are grieving, and survivors have lost everything.”


Land mines and tuberculosis are no match for Tanzanian ‘hero rats’ sniffing out danger and disease

Land mines and tuberculosis are no match for Tanzanian ‘hero rats’ sniffing out danger and disease
Updated 04 September 2025

Land mines and tuberculosis are no match for Tanzanian ‘hero rats’ sniffing out danger and disease

Land mines and tuberculosis are no match for Tanzanian ‘hero rats’ sniffing out danger and disease
  • For decades APOPO has trained these “hero rats,” which have one of the most sensitive noses in the animal kingdom
  • Since 2003, the rats have been finding land mines and, more recently, have been turned on to trafficked wildlife and earthquake survivors

MOROGORO: A man lies unmoving, slumped in the rubble of a simulated earthquake, as an unlikely rescuer approaches: a rat with a backpack. Whiskers waving, the rat breezes past garbage, toppled furniture and scattered clothes to find him and pull a trigger on its pack, alerting searchers above.
Then a resounding click. A survivor has been found. The search in Morogoro in Tanzania’s Uluguru Mountains is over and the rat scurries out of the abandoned building to be rewarded with a banana. A successful mission is complete for this African giant pouched rat being trained for search and rescue operations.
“Their sense of smell is incredible,” said Fabrizio Dell’Anna, an animal behaviorist at APOPO, a Tanzania-based nongovernmental organization that trains the rats for lifesaving applications. “These rats are able to detect explosives, tuberculosis — even tiny amounts of the bacteria — and in this project, they are able to correctly identify and indicate humans.”
In a field nearby, more rats walk on leashes held between handlers, pacing a grid filled with land mines as part of an initiative by APOPO, which works alongside Sokoine University of Agriculture. When they pause, it indicates that explosives are beneath. These rats are readying for their next deployment, perhaps Angola or Cambodia, where APOPO has helped clear more than 50,000 land mines since 2014.
From detecting land mines to sniffing out tuberculosis, these “hero rats” have become unlikely, and sometimes unrecognized, front-line responders in Tanzania and beyond.
Trained ‘hero rats’ with sensitive noses
For decades APOPO has trained these “hero rats,” which have one of the most sensitive noses in the animal kingdom. Since 2003, the rats have been finding land mines and, more recently, have been turned on to trafficked wildlife and earthquake survivors.
The rats begin training shortly after birth for specific missions and, with a longer-than-average rodent life span of almost a decade, can spend years carrying out their work. The cost of training each rat runs around 6,000 euros ($6,990).
It is all done with classical conditioning and positive reinforcement, explained Dell’Anna, who oversees the search and rescue program. The first cohort of this group of specialized rats are already in Turkiye with a partner search and rescue organization.
Helping the global fight against TB
While the rats focused on explosives or survivors buried in rubble get all the glory, it is a group of rats inside a lab that are arguably the most impactful lifesavers. These are not typical lab rats, but rather, as their proponents would argue, one of the world’s most effective detectors of tuberculosis.
“Every day as many people die from TB as from land mines in a whole year,” said Christophe Cox, the CEO of APOPO. “It’s more spectacular to be on the minefield … but for TB … in terms of social impact, it’s tremendous.”
Tuberculosis is an ancient respiratory disease that continues to run rampant despite centuries of research and treatment. The World Health Organization said last October in its most recent TB report that the disease had resurged as the top infectious disease killer, with 1.25 million deaths and a record 8.2 million infections in 2023.
In sub-Saharan Africa, only about half of TB patients receive a diagnosis, according to a study by researchers in the UK and Gambia published in the National Library of Medicine, and this leaves them liable to spread the disease. Tanzania struggles with one of the highest global TB burdens, according to the WHO.
APOPO expanded into TB detection in 2007 and its rats have been deployed in Tanzania, Ethiopia and Mozambique. The group works with 80 hospitals in Tanzania, collecting samples daily and bringing them to the lab rats.
With their sensitive noses, the rats sniff out samples of sputum from patients, looking for positive TB cases that had been marked as negative. Research suggests the rats are picking up on six unique volatile organic compounds in positive TB samples, said Cox.
False negatives remain a persistent issue in TB detection and suppression because each infected person can spread the disease to 10 to 15 more people each year.
“The benefits of using rats are significant,” said Felista Stanesloaus, a doctor at a TB clinic in Morogoro. “They help us detect cases that might otherwise be missed, which prevents people from unknowingly spreading infections.”
Making TB detection accessible
TB detection has made significant advances in recent years, including using artificial intelligence tools in conjunction with lung scans. However, many areas that are burdened most by TB, such as rural villages or low-income urban communities, do not have access to these tools.
While the use of molecular detection devices, such as one called GeneXpert, have become more widespread, a clinic may only have one of these devices and it can take two hours to process a sample. Overburdened clinics turn to the centuries-old technique of microscopy, or investigation of sputum under a microscope, which is both fallible and time-consuming.
“Human error may result in a person being told they are disease-free when they are not,” said Stanesloaus. “Using rats is a very effective initiative.”
APOPO’s rats can scan 100 samples in 20 minutes, and since the program’s inception, the rats have been able to identify more than 30,000 patients who had been sent home with a clean bill of health but were actually carrying TB, said Cox. The NGO is able to do with one lab what 55 hospitals do in a day, he adds.
Yet using live animals in the place of medical devices poses challenges, especially when it comes to scale. Samples have to be brought directly to a lab with enough trained rats to conduct the detection, with some samples brought to Morogoro by motorbike each day. Operations are most effective in dense urban centers, like Dar es Salaam, Cox said.
Meeting WHO standards
The more existential challenge for these “hero rats” comes from regulators and a wider health community who doubt this unconventional method of disease detection.
APOPO’s rats are not classified as primary diagnostic tools by the WHO. Instead, they are a second line of defense. Any positive samples detected by the rats must be confirmed with human microscopy in APOPO’s labs before treatment can be administered.
“It’s a big challenge,” said Cox. “Not being recognized by the WHO means that the mainstream funding for TB … never reaches us.”
Cox has given up on the prospect of getting approval from the WHO, though APOPO has faced pressure from donors to go through this process, which would be extensive and rigorous with no guarantee of success.
Regulators may also challenge APOPO’s method of focusing on finding every single positive case possible at the cost of more potential false positives.
APOPO relies on the indication of just one rat to proceed with further investigation into a possible positive case, while higher specificity standards may need multiple rats to flag a sample.
Cox defends this approach.
“Our choice was to go for that last patient out there — to go for the social impact,” said Cox.